The Constitution wasn't responsible for the death of liberty in America. We are.
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The death of Liberty was gradual - every generation (including the founding generation) 'compromised' a little bit. The Constitution was a large increase in central government power at the expense of that recently hard-won Liberty. Read Lysander Spooner's "No Treason" for a better understanding of the problem. When you 'compromise' away a little bit of Liberty at a time for a long enough time, you lose it all; the Grand Canyon is an excellent physical example of the process.
By the middle of the nineteenth century, enough damage had been done that the Second American Revolution became inevitable. That one did not turn out so well, but, as the old expression has it, "The third time's the charm." Coming soon to a town near you...
That's what I said. "We" are. As in, "We the People". Through compromise and folly and ignorance and selfishness.