375 socom is a good option for hunting. Flatter shooting than the 458 and shots out to 300 yards are much more realistic with it, so it can be considered a bit more practical. Works with standard AR mags too.
Downsides:
1) Brass costs slightly more than 458, but is directly available from SBR ammo.
2) Less bullet variety and factory loading offerings than other big bores.
3) Cost prohibitive without reloading (like every big bore).
4) It's not as big as 45 or 50 :)
Anyway, this came in yesterday from Tromix. I'm looking forward to subsonic load development.
https://i.imgur.com/TFHPQla.jpg?2