Twenty years ago, Philadelphia's Osage Avenue was the site of a stunning use of force by city police. After a long standoff, police dropped a bomb on the headquarters of a radical group called MOVE, sparking a fire that gutted a neighborhood and left 11 people dead. Five were children.
I'm not 100% convinced that the satchel charge was the primary cause for the fire. I am of a mind that the fire may have been set inside, as a strategic measure by the MOVE folks to garner support against the city/PD, and it went horribly wrong. Still, the bomb was a 4lb satchel charge of tovex (?) and C4. Dropped on a row house, in a crowded Philly neighborhood. Wow.