Social Issues
Stay the fuck away from abortion, gay rights, or anything to do with the pill. That stuff's a third rail that will drive away libertarian types and moderate voters, and is the Democrat equivalent of the Bat Signal.
Weed:
1.) Whatever it was that Morse was dragging his feet on regarding Amendment 64, get rid of it, and institute the will of the people.
2.) Get behind the bill to allow dispensaries access to financial institutions.

-This helps build a coalition with some of the hippy-libertarian types, and also allows them to play the "job creator" card, even if those jobs aren't the sort of thing a typical Republican would approve of.
Both of these are key to making sure that the republicans can gain a larger following with independents and more libertarians. We should push to repeal the idiotic gun legislation pushed through this last year, especially with the backing of the sheriffs that were there to stand against the bills, it would be possible to repeal these bills. They only won by a narrow margin anyways.