I had a Ruger 22/45 that had close to 7k-8k through it. Never failed me once with regular maintenance. I recently purchased a Ruger SR22 and have had 0 problems with it but it only has about 500 though it.
"But when it's time to fight, you fight like you are the third monkey on the ramp to Noah's Ark; and brother, it's startin' to rain."