That has to be an individual decision. What type of effort are you willing to put out? What types of risks are you willing to take with your ability to provide for your family and maintain your freedom?
At the very start, you can keep yourself informed about the current activities of both houses of Congress at the state and national levels. When you see they are treading down a road that you are not comfortable with, contact them via eMail and telephone and get the word out to everyone you know that might share your view on the matter and encourage them to do as you did.
You could consider forming or joining political action groups.
The scale of things you can do continues to go up to more serious actions. Participating in or staging protests to outright civil disobedience.
I know someone who is a bit older and retired. This individual has clearly stated that, should the Blair Holt bill pass into law, they will refuse to abide by the law. This person is aware that they will be convicted (notice I said nothing about being charged or prosecuted) if found out. That is a risk this person is willing to take - and is hoping that millions of others are willing to take that same risk. Our current penal system could not accomodate that number of incarcerations. The problem with this train of thought is, while you may not go to prison, you would have a felony on your record which will effect job possibilities, etc.
Know that I'm not encouraging anyone to take any of the more severe actions, but I certainly encourage you to get involved politically and remind our elected officials that they work for us.
ETA [Edit to Add]: My system overheated and crashed and I just took too long to post this message. In the mean time the above post from RRD3 came in saying very similar things. I apologize for stepping on your feet.