PSA PA10 upper + LR308 lower = charging handle may not clear buffer tube yoke.

Personal experience. Two separate uppers and lowers. Interference of ~.030". Coworker removed material from yoke on his. He is running it.
I was not comfortable going that route, as I felt there was some mis-alignment between bore axis and buffer tube axis.
The upside?

I now have a complete PA10 and a complete non PA10. Had tight-chamber issues with my PA10, but that was addressed and now runs smoothly & reliably. Had no issues with other setup.