Absolutely.
There are several videos of folks completing these with simple tools.
One guy completed one on his bathroom counter with a dremel, some sandpaper, and a cordless drill. Another guy did it in like 30 min with a hand drill, some box end pliers and some sandpaper.
I've been looking at doing one. Just wanted a .22. Thinking that lower with one of the .22 slide kits would do the trick.