Bottoming out your scope is no fun. A xmas tree reticle can help in this case, but depending on various factors, it cannot hurt you unless the travel available from center is suddenly not enough to allow you to bring it on zero w/ the elevated base. At which point you have to increase your zero range and hold under on closer targets.

Some of this stuff can be mitigated with flatter shooting calibers.

Personally, I always run an elevated base.