I realize this is anecdotal on its own, though I’ve heard so many similar anecdotes at this point that I’m unconvinced they are, together, able to be hand waved away.

One of the families at church have a HS senior who desired to go on a mission trip to Peru. She had to get the typhoid vaccine. Within a minute of receiving the vaccine she started having a reaction. Doctor’s office shuffled them out in a hurry. She now has adult onset asthma, previously never having any issues of that sort. So instead of just risking the typhoid and resultant treatment, she now has a lifelong condition seemingly brought on by a rather needless vaccine.