I run a SilencerCo Omega on my 300WM elk gun and the brake on the end is fairly efficient at taming it down. It also runs on my 6.5CM when I shoot some comps and I am happy with how it performs.

I have several .22 cans and like the EA NYX Mod2 over my SilencerCo Sparrow. The NYX is smaller diameter then the Sparrow. I would recommend on the .22 can, a titanium or stainless steel for ease of cleaning and longevity since it is a "lifetime" investment.