I have looked into these cartridges.
22 Nosler - I'm skeptical my Terminus action could handle the rebated rim. As the case rides up the feed ramp and the base of the cartridge drops slightly down into the magazine, I suspect the rim will drop below the bolt face resulting in feed issue.
224 Valkyrie - My Terminus action only offers bolt faces supporting 308 & 223 cases. There's also an issue of mags. I've only found polymer AICS mags for the Valk and the few polymer mags I've tried won't allow the bolt to even move forward in the Terminus. This appears to be related to the extra thick polymer feed lips.
22 creedmoor - I dismissed this cartridge as a barrel burner.
22-250 - Also dismissed this as a barrel burner but there's also an issue of cartridge length. I need a cartridge at least 2.45" or more to feed reliably in the Terminus action. It's possible I could achieve this with heavy 22 bullets which is what I intend to shoot but never pursued it.