Are there Grizzlies in the lower 48? That's the only thing that would cause me to feel underarmed. Lions are thin skinned, so a .357 should be strong medicine.

I ran a black bear out of my yard a year or so ago with a lightweight J frame in my hand loaded with .38 +P's. I felt reasonably secure knowing (hoping) he would run, and if he didn't I'd get a chance to see what effect 5 rounds would have at contact distance.