I like the P-22. There are reports of the P-22 being picky about ammo, so far mine has eaten everything I've fed it so I guess I'm just lucky.
I tried the S&W 22A and didn't like it. It was picky about ammo and I didn't like the sights. It comes with an integrated rail for a scope but I never mounted one.
My favorite .22 is a S&W revolver. Smooth trigger and I hit a rabbit in the head at 40 yards with it (I then missed one at 10 yards but that's not the important part of the story).
I've shot a Buckmark and Ruger. I only put 60 rounds through each and for me they were indistinguishable. They are good for targets and as a hunting side arm for small game.