In my experience, stay away from the East side of town, Southeast specifically. Pueblo has developed a rather large gang problem in recent years, but like most places, if you don't gang bang, you don't usually have any problems. If it were me, I would prefer to live in Pueblo West. Take my opinion for what its worth, I haven't spent much time in Pueblo over the last 5 or so years, but I am from La Junta, so I have spent my fair share of time in Pueblo over the years.