^^^^ This is the winner ^^^^
I live in Denver proper (but, really, let's be real here, I live on the border of Denver and Lakewood, not exactly the hood) and go to LoDo all the time at night to eat at some of my favorite restaurants and hang out doing some people watching. LoDo is a pretty safe place in this situation but I'm not going to wander around off the beaten path because I know it's looking for trouble. When I'm forced to because of where I parked or whatever, then I see every single person as a threat and avoid any situation that might get ugly.
There is one side of me that says if someone had thrown a bottle and hit my girl in any way and hurt her in any way my Apeshit light would go on and I would confront them with no regard to my own personal well being. The other side of me says that it's best to get her to a hospital as soon as possible, note everything about the situation and get the cops involved because I know that A) I would probably shoot somebody, B) probably get charged with something, C) might compromise myself and get my wife raped and/or D) get myself killed.
I can hope that the Army training I went through years ago would kick in and keep me safe but I really can't be certain of that and it's not just my life but the life of my girl that I could put on the line to test it. One-on-one or two I can likely handle, but three or more is probably pushing it.