Eliminate the departments of Education, Agriculture, and HUD entirely. Along with all of HHS except for CDC. (Who would sort of exist, but just to deal with pandemics and not to do bullshit sociological research.)

Eliminate DHS, Fold Customs back into Treasury, FPS back into GSA, INS/BP back into Justice, USCG back into Transportation. BATFE, TSA, and DEA would go away entirely.

Every other department will take sharp cuts. In the end, the Federal government will have a balanced budget requirement and will not be allowed to have multi-year debt. I'm not an isolationist, and I like defense, but fixing our fiscal house will require cuts from DoD as well.

Privatize the USPS (or declare it to be private and independent whether it wants to be, or not)

SS taxpayers would be given the option to opt out: waive all claim to money already paid, and never pay again. Ditto Medicare.

All individual income and capital gains taxes flattened. I'm thinking 15% but I'm not in love with any number that isn't a sharp decrease. Most if not all deductions and credits would be eliminated.

Get the Federal government out of the prohibition business. If some state wants to punch holes in the Fourth Amendment and give a what's basically a price-support subsidy to MS13, that's their problem. They shouldn't be able to drag other states down with them. Federal gun control would also go away.

Pull the plug on the NLRB: labor relations are something for labor and management to work out for themselves. If an employer does not wish to deal with a union, that employer will not be forced by law. I would also end collective bargaining in the Federal government.

An end to every Federal subsidy: TARP, auto bailouts, Section 8, food stamps, etc. And as for banking, it would remain illegal to commit fraud in interstate commerce, but banks could make the loans that they want to make, refuse the loans that they don't, and go broke and out of business if they insist on making negative-equity interest-only mortgages on stated income only.

Oh, and the death penalty for taking the last ice cube out of the freezer and not refilling the ice tray.