office pranks are fun.
I changed a d-bag coworker's MS Office Suite (PPT, Outlook, Word, Excel, etc.) so that every time he entered a period, it changed to ". In accordance with the prophesy, " . . . That way whenever he started a new sentence in started with that nifty little phrase. He found out about a week later, which might as well have been a decade.
I also changed his email signature line job title to Pretty Boy. He also didn't figure that one out for about two weeks. He couldn't figure out why all the higher ups kept calling him pretty boy.