And I've seen cases where a primary argument of the prosecution was excessive use of force because shots were fired after the perceived threat was "stopped".
Same can be said of .45.
It was developed as an anesthetic so that'll give you an idea of it's affects. Seems to me that a hit to the CNS would be the best bet in a situation like that. Again, shot placement is king with bullet size being secondary. That said, if I'm in that situation, I'm not going to be able to consciously think to shoot to hit the CNS. I'll be shooting COM until the threat stops.
I'm a strong believer in the best round being the one that you can get positive hits with and have with you when needed.









